What's Included
- Early pregnancy scan
- Blood sample collection during appointment
- Personalised risk report within approximately 10 days
Screen for rare but significant genetic conditions
Advanced NIPT testing, Panorama™, uses a simple blood draw to assess your baby’s risk for chromosomal conditions and determine sex. It screens for common trisomies, triploidy, and 5 microdeletions, including 22q11.2 (DiGeorge syndrome) and other chromosomal conditions that standard screening misses. This package includes an early pregnancy scan. Optional sex determination.
Highly accurate screening, 99% combined sensitivity for trisomies
SNP-based Panorama technology
Results in 7-10 working days
Microdeletion Panel
An advanced screening option that looks for small missing pieces of chromosomes (microdeletions) that cause conditions like DiGeorge syndrome, Prader-Willi, Angelman, 1p36 Deletion Syndrome and Cri-du-chat.
Common trisomies (Down Syndrome, Patau and Edward Syndrome), triploides and sex aneuploides included.
Optional sex determination included.
It inlcudes a scan on the day of the blood draw.
From
0 weeksDuration
0 minutes
Price
£ 650
Results
7-10 days
What's included
Screening beyond standard chromosomes
Advanced testing for conditions that basic NIPT doesn't detect
22q11.2 deletion (DiGeorge syndrome)
The most common microdeletion, occurring in approximately 1 in 2,000 births regardless of maternal age. Associated with heart defects, immune problems, and developmental differences.1p36 deletion syndrome
A condition affecting approximately 1 in 5,000-10,000 births, causing intellectual disability, distinctive facial features, and often heart defects.Prader-Willi and Angelman syndromes
Conditions caused by deletions in chromosome 15, each affecting approximately 1 in 15,000-20,000 births with distinct developmental impacts.Cri-du-chat Syndrome
Caused by deletion on chromosome 5, affecting approximately 1 in 20,000-50,000 births. Named for the distinctive cry in affected infants.Angelman Syndrome
Angelman syndrome happens when either a small piece of chromosome 15 is missing, or when both copies of chromosome 15 come from the same parent (called uniparental disomy, or UPD). About 1 in 12,000 babies are born with Angelman syndrome. Babies and children with Angelman syndrome have severe intellectual disability, delayed milestones, seizures, and problems with balance and walking.SNP-Based Technology
Panorama's SNP-based approach distinguishes fetal DNA from maternal DNA more precisely, reducing false positives compared to counting-based methods.
Complete Service Overview
Your NIPT Microdeletion Panel—Explained
A non-invasive blood test from 9 weeks that screens for common chromosomal conditions plus five microdeletion syndromes. Analyses placental DNA using SNP-based technology, with results in approximately 10 days.
Who is this for?
- Those wanting comprehensive genetic screening beyond standard NIPT
- Parents seeking screening for microdeletion syndromes
- Those with a family history of chromosomal conditions
- Anyone wanting non-invasive genetic assessment from 9 weeks
- Those preferring detailed risk information before deciding on further testing
- Those wanting comprehensive genetic screening beyond standard NIPT
Technical Details
- Screens for Trisomy 21, 18, and 13 with over 99% sensitivity
- Includes 5 microdeletions: 22q11.2, Prader-Willi, Angelman, 1p36, Cri-du-chat
- Also screens for sex chromosome conditions and triploidy
- 83% sensitivity for 22q11.2 deletions
- Not suitable for triplet+ pregnancies or bone marrow transplant recipients
- Screens for Trisomy 21, 18, and 13 with over 99% sensitivity
What to expect
Your appointment, step by step
Before Your Appointment
- Book online—available from 10 weeks
- No fasting required
During Your Appointment
- The sonographer will perform a scan to confirm viable pregnancy
- Simple blood draw (same sample as standard NIPT)
- 15-20 minutes total appointment time
- We’ll explain the benefits and limitations of teh screening
After Your Appointment
- Results in 7-10 working days
- Written report will be sent to you via email
- Genetic counselling support available if needed
- If results are inconclusive, a free redraw may be offered depending on clinical context: we will contact you to confirm.
Why choose Flowan Health
Every test comes with the time to answer your questions, explain what we find, and make sure you understand your results—not just receive them. That's why mothers who want comprehensive genetic information trust us.
What you get | What this means for you | |
|---|---|---|
| Advanced analytics | ||
| From 10 weeks | Early, comprehensive screening | |
| Panorama SNP technology | More accurate fetal DNA dedetection | |
| Screens conditions missed by basic NIPT | Beyond standard trisomy screening | |
| Results in 7-10 days | Timely information for decision-making | |
| Genetic counselling access | Support to understand your results | |
| 5.0/5.0 from 467+ reviews | Unmatched service and attention | |
Online booking at 2am or 2pm - we're ready when you are
Take the first step towards comprehensive and compassionate healthcare tailored for women.
Common questions about microdeletion screening
Understanding advanced genetic screening. Here's what you need
to know.
What is a microdeletion?
A microdeletion is a small missing piece of a chromosome—too small to see on standard chromosome analysis but large enough to affect health. Most microdeletions happen randomly and aren’t related to maternal age, which is why they’re worth screening for at any age.
Why isn't this included in standard NIPT?
Standard NIPT screens for whole chromosome conditions (trisomy 21, 18, 13) which are relatively common and have high detection rates. Microdeletions are much rarer (except 22q, which is already included in our basic NIPT Panorama test). They are also harder to detect accurately. Not all NIPT providers offer microdeletion screening, and those that do use different technologies with varying accuracy.
How accurate is microdeletion screening?
Microdeletion screening has a higher false positive rate than standard trisomy NIPT—meaning a “positive” result needs confirmation. Detection rates vary by condition (typically 70-90%), and positive predictive value is lower than for trisomy screening. NIPTs are screening tests, therefore despite highly accurate, they are not 100% certain and diagnostic. Where high risk is detected you can discuss with your maternity care diagnostic invasive next steps
What happens if a microdeletion is detected?
A positive screening result doesn’t confirm a diagnosis—it indicates increased risk. Share results with your maternity care provider to discuss your options for diagnostic testing (CVS or amniocentesis) to confirm or rule out the finding. Additionally, genetic counselling is available with our partner laboratory to better understand your results and implications.
Should everyone have microdeletion screening?
This is a personal decision. Some parents want the most comprehensive screening available; others prefer to screen only for more common conditions. The key consideration is that microdeletions are rare but occur regardless of age, so if you would want to know about these conditions, age alone isn’t a reason to skip this screening.
What's the difference between Panorama and other NIPT tests for microdeletions?
Panorama uses SNP-based technology that can distinguish fetal DNA from maternal DNA more precisely than counting-based methods. This matters for microdeletion screening because it can reduce false positives. Not all NIPT providers use this technology
Does NHS offer microdeletion screening?
Microdeletions are not part of the standard NHS antenatal screening programme in England.
Happy stories from Parents
Real experiences from those who trust our care.
The staff are great and the service is impeccable. Lauren the sonographer is empathetic, personable and so kind which made our 8 week scan a wonderful experience
I’ve visited Flowan a few times over the last few years for various reasons and every time the service and care is outstanding. There are clinics much closer to me I could opt for but travel out of my way to Flowan simply for the service.
Felt safe and comfortable at this clinic! Very good service, would recommend!!
We came for an early pregnancy scan. Such lovely, professional staff at the clinic. Explained everything super clearly and were so friendly! Would really recommend.
The team are so friendly and helpful, really excellent service. We asked not to see the gender of the baby but for it to be part of the surprise package and we couldn’t be happier!! Such a lovely experience seeing our baby
